Blast Works is a cross between a side-scrolling shooter mixed with a bit of Katamari. The main objective of the game is to destroy as many enemies as you can, collecting the pieces of the destroyed enemies to build onto your ship to make it more powerful.

There is a main mission mode with over 15 different missions or players can play non-stop with a Marathon mode. There is also a level editor and a ship editor as well, letting players create their own levels with as many or as few enemies and create their own ships, along with their own special weapons and bullet spread pattern.

It can support up to four player simultaneously and players have the ability to go online and trade ships and levels and show off their high scores. Can be played with the Wii remote and Nunchuk along with the classic controller and players can unlock TUMIKI Fighters, which served as inspiration of the game and where most of the game mechanics are borrowed from, once the game is completed.