Lego Pirates of the Caribbean: The Video Game is a game based on the four popular movies; The Curse of the Black Pearl, Dead Man's Chest, At World's End and On Stranger Tides. This game mixes these movies with the child-friendly Lego style of other Lego games, but for the most part everything is still the same. The player takes control of characters like; Jack Sparrow, Elizabeth and Bootstrap and uses their special abilities to solve the puzzles. Most of the puzzles require the player to build items with Lego-bricks or to open locked doors, aside from the character that are available the player can also take control of animals like a dog or a bird. The story allows the player to choose on of the four movies and a chapter to play, each movie has four chapters.

It starts out with the pirate "Jack Sparrow" and the blacksmith "Will Turner" meeting each other and dueling, after Jack failed to beat Will and is put in prison the ship known as "The Black Pearl" arrives at the port and raids the city. Will frees Jack after his love, Elizabeth got captured by the pirates. Jack and Will steal a ship from the navy and take it to the pirate city Tortuga where they assemble a crew and follow The Pearl to where they are taking Elizabeth.