Scooby, Shaggy, Fred, Daphne and Vilma arrive at 'Mystic Manor' to meet Daphne's friend Holly. There she explains that her inventor-uncle is missing. Soon the rest of the gang ends up missing too and alone as Scooby you must find them all, and along the way solve the mystery of the Mastermind. This guy has brought back the gangs old fiendish villains and is probably the cause of all the havoc.

The levels have you running, jumping and swinging around, all the while taking out baddies, collecting scooby snacks and finding secret passages. You also have to locate special inventions scattered around the place, that can give Scooby extra capabilities.