Uncharted: The Lost Legacy is a side story game built on the same engine as Uncharted 4. It focuses on the supporting character of Chloe Fraser, previously seen in three installments of Uncharted. The story takes place several months after the events of Uncharted 4. In order to recover an ancient artifact - the Golden Tusk of Ganesh - Chloe with the assistance of Nadine Ross travel to India. They are not alone in their search for the item, and pretty soon they will find out that there is someone they both know also involved in.

The game consists of nine chapters with a prologue and epilogue. The controls and mechanics are exactly the same as in Uncharted 4, as well as having a collectibles system that gives the possibility to unlock the extra content.

The multiplayer option and survival modes are also included, and they are the same as in Uncharted 4.