The DS version of WWE Smackdown vs. Raw 2008 is quite similar to the main console versions and contains many of the other version's features. This edition contains a roster of over 20 WWE superstars. Also the game takes full advantage of the touch screen, using it to control your superstar during jumps, grapples and more.

There are many different arenas such as SummerSlam, WrestleMania, and the superstars from Smackdown, Raw and ECW, including the Sandman, Jeff Hardy and exclusive to the DS version, Hardcore Holly. There is a full season mode and selection of mini-games to train the fighters.